Statistical tests
Fisher's exact test p-value calculator, 2x2 and 2x3
mid-p adjustment
P-value:
Hardy-Weinberg equilibrium exact test
heterozygote count
homozygote count 1
homozygote count 2
mid-p adjustment
P-value:
Exact binomial test
successes
total observations
expected success rate
Alternative hypothesis:
P-value:
These JavaScript calculators employ an accelerated, memory-efficient version of the logic used by the Abecasis Lab's SNP-HWE software. See the PLINK core algorithms page for some discussion.
You can use PLINK 1.9's --hardy, --hwe, and --assoc/--model commands to apply these functions to large genomic datasets.
You are welcome to use this page's JavaScript code in your own software (under GPLv3 terms). C/C++ versions of these functions can be obtained from the GitHub repository.